P. Traine , C. Scheib, J. Garweg Spacer element

Choroidal Neovascularization Resulting from Angioid Streaks in Pseudoxanthoma Elasticum

A 31-year-old woman demonstrated decreased vision in her left eye at presentation. Visual acuity was 16/20 in this eye. A, Funduscopy revealed angioid streaks with a small parafoveal hemorrhage. B, OCT showed parafoveal hyperreflective subretinal material associated with minimal subretinal fluid. C, Fluorescein angiography confirmed a choroidal neovascular membrane. D, Fundus autofluorescence showed associated optic disc drusen. On clinical examination the patient showed papular lesions of the neck and the axillae, confirming the suspicion of pseudoxanthoma elasticum. Four weeks after a single intravitreal injection of ranibizumab, subretinal fluid had resolved completely with recovery of visual acuity to 20/20.

2019, Ophthalmol Retina, 3(1):31. doi: 10.1016/j.oret.2018.10.007. PubMed PMID: 30929814

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